CHANGES IN GENE EXPRESSION PATTERNS IN THE TUMOR MICROENVIRONMENT OF HEAD AND NECK SQUAMOUS CELL CARCINOMA UNDER CHEMORADIOTHERAPY DEPEND ON RESPONSE

Chemoradiotherapy (CRT) is a standard treatment for advanced head and neck squamous cell carcinoma (HNSCC).Unfortunately, not all patients respond to this therapy and require further treatment, either salvage surgery Tumbler or palliative therapy.The addition of immunotherapy to CRT is currently being investigated and early results describe a mixed

Head and neck cancers are highly prevalent worldwide.Most of these lesions are diagnosed in the advanced stages of the disease.Thus, they do not often have a good long-term prognosis.Like other cancer types, head and neck cancers are managed by surgery, radiotherapy, and chemotherapy.Despite significant advances in the treatment of oral squamous ce